The Omicron variant of COVID-19 is 4.2 times more transmissible in its early stage than Delta, according to a study by a Japanese scientist who advises the country鈥檚 health ministry, a finding likely to confirm fears about the new strain鈥檚 contagiousness.

Hiroshi Nishiura, a professor of health and environmental sciences at Kyoto University who specializes in mathematical modeling of infectious diseases, analyzed genome data available through Nov. 26 in South Africans in Gauteng province.

鈥淭he Omicron variant transmits more, and escapes immunity built naturally and through vaccines more,鈥 Mr. Nishiura said in his findings, which were presented at a meeting of the health ministry鈥檚 advisory panel on Wednesday.

Concerns are swirling globally that Omicron could deal the world a bigger blow than even Delta, and the World Health Organization (WHO) has cautioned that it could fuel surges with 鈥渟evere consequences.鈥 But a jump in cases in South Africa in the wake of the variant鈥檚 emergence hasn鈥檛 yet overwhelmed hospitals, leading to some optimism that it may only cause mostly mild illness. Pfizer, Inc. and BioNTech SE also said this week that a booster dose of their vaccine could fortify protection against the strain.

Mr. Nishiura鈥檚 study hasn鈥檛 been peer-reviewed and published in a scientific journal. The new analysis was conducted using the same method he used in a July study published by the Eurosurveillance medical journal on Delta鈥檚 predicted dominance ahead of the Tokyo Olympics.

Hundreds of researchers globally are racing to understand the new variant, which is the most differentiated strain yet among the five variants of concern identified by the WHO since the pandemic began.

Cases in South Africa have rapidly increased to as many as nearly 20,000 a day since the country first reported Omicron鈥檚 discovery two weeks ago. The number of COVID cases in the nation had remained low in the preceding weeks, despite only 26% of the population being fully vaccinated, according to Bloomberg鈥檚 Vaccine Tracker.

鈥淭he vaccination rate was less than 30% and many people were probably naturally infected,鈥 Mr.聽 Nishiura said. 鈥淲e need to pay close attention to future trends to see if the same thing will happen in countries where mRNA vaccines are used at a high rate.鈥 鈥 Bloomberg